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Reactor Explosions and Runaway Reactions

Reactors are among the highest-consequence equipment items in chemical and petrochemical plants — loss of containment or temperature control can quickly escalate to explosions or uncontrolled reactions. These investigations detail the precursor conditions, safeguard failures, and systemic factors the CSB found in each event.

16 CSB investigations in this database involve reactor as a primary or contributing equipment factor, spanning 1998–2024.


Reactor Explosions and Runaway Reactions (16)

Incident Date Industry Key Hazard
T2 Laboratories Inc. Reactive Chemical Explosion 12/19/2007 Chemical Manufacturing Runaway Reaction, Thermal Runaway
Valero Delaware City Refinery Asphyxiation Incident 11/05/2005 Petroleum Refining Asphyxiation
Bayer CropScience Pesticide Waste Tank Explosion 08/28/2008 Chemical Manufacturing Runaway Reaction, Explosion
LyondellBasell La Porte Fatal Chemical Release 07/27/2021 Chemical Manufacturing Chemical Release, Toxic Release
Kuraray Pasadena Release and Fire 05/19/2018 Chemical Manufacturing Chemical Release, Fire
Husky Energy Superior Refinery Explosion and Fire 04/26/2018 Petroleum Refining Explosion, Fire
Formosa Plastics Vinyl Chloride Explosion 04/23/2004 Chemical Manufacturing Explosion, Fire
MFG Chemical Inc. Toxic Gas Release 04/12/2004 Chemical Manufacturing Runaway Reaction, Toxic Release
Yenkin-Majestic Resin Plant Vapor Cloud Explosion and Fire 04/08/2021 Chemical Manufacturing Vapor Cloud Explosion, Explosion
Morton International Inc. Runaway Chemical Reaction 04/08/1998 Chemical Manufacturing Runaway Reaction, Thermal Runaway
KMCO LLC Fatal Fire and Explosion 04/02/2019 Chemical Manufacturing Vapor Cloud Explosion, Flash Fire
Union Carbide Corp. Nitrogen Asphyxiation Incident 03/27/1998 Chemical Manufacturing Asphyxiation, Toxic Release
BP Amoco Thermal Decomposition Incident 03/13/2001 Chemical Manufacturing Chemical Release, Explosion
ExxonMobil Torrance Refinery Explosion 02/18/2015 Petroleum Refining Explosion, Fire
Synthron Chemical Explosion 01/31/2006 Chemical Manufacturing Runaway Reaction, Vapor Cloud Explosion
Silver Eagle Refinery Flash Fire and Explosion and Catastrophic Pipe Explosion 01/12/2009 Petroleum Refining Flash Fire, Explosion

Chemical Release · Fire · Explosion · Overpressure · Runaway Reaction


Valve Failures in Process Plant Incidents · Pressure Vessel Explosions and Failures · Relief Valve Failures and Overpressure Events · Pipeline Ruptures, Leaks, and Fires · Vent Stack Failures and Release Incidents · Gas Detector Failures and Toxic Release Incidents


Data sourced from CSB.gov public investigation reports. This site is an independent project not affiliated with the U.S. CSB.